Non-GYN Cytology

 

 

A Non-GYN cytology requisition form complete with the patient’s full name and date of collection must accompany all Non-GYN cytology specimens.  We provide containers upon request. 

 

Sputum                 

Proper collection and fixation is essential for good diagnostic material.

·         The optimum time for specimen collection is within 15 to 30 minutes after waking and before eating breakfast.

·         Instruct the patient to brush teeth and/or rinse mouth thoroughly with water to reduce saliva contamination. 

·         Instruct the patient to inhale and exhale deeply, forcing air from lungs, using the diaphragm.  Repeat until the patient coughs and is able to produce a sputum specimen.

·         Collect the specimen in a clean specimen container. As soon as possible, add an equal volume of CytoLyt Solution.

·         Label the container with the patient's full name. Submit to the laboratory with the completed requisition form.

 

Bronchial specimens

Using standard bronchoscopic technique, identify the lesion in question.  Obtain a brushing sample of the lesion and/or lavage the area to be sampled.  Identify location of the lesion on the container and/or smear when submitting multiple specimens.

·         Bronchial brushings:

If requesting evaluation for microorganisms, submit direct smears: Roll brush across a slide labeled in pencil with the patient's full name.  Do not fix.  Allow to air-dry.  Deposit the brush directly into container of CytoLyt Solution labeled with the patient’s full name and submit to the laboratory with the completed requisition form.

·         Bronchial washings:

Collect in a clean container labeled with the patient’s full name.  Immediately add an equal volume of CytoLyt Solution.  Submit to the laboratory with the completed requisition form.  

·         Bronchial lavage (BAL):

Collect in a clean container labeled with the patient’s full name.  Immediately add an equal volume of CytoLyt Solution.  Submit to the laboratory with the completed requisition form.  (BAL specimens for culture need to be split prior to adding the fixative.) 

 

Urine

Urine specimens must be properly collected. The method of collection must be indicated, i.e. voided, catheterized, cystoscopic (bladder wash-irrigation), etc.

·         Female patients must cleanse the urethral/genital area to avoid contamination with squamous cells.

·         Obtain a midstream clean catch voided specimen.

·         Collect in a clean container labeled with the patient’s full name. Immediately add an equal volume of CytoLyt Solution.  Submit to the laboratory with the completed requisition form.

 

Other Body Fluids - Pleural, Pericardial, Pelvic and Peritoneal            

·         Collect in a clean container labeled with the patient’s full name.  Add an equal volume of CytoLyt Solution, or make sure the specimen is refrigerated.  Submit to the laboratory with the completed requisition form.

 

Nipple Discharge

·         Direct Smears: Express nipple discharge fluid onto a slide labeled in pencil with the patient's full name.  Immediately fix with an alcohol base spray fixative.  Submit to the laboratory with the completed requisition form.  Do not massage or squeeze the breast; too vigorous manipulation may dislodge and spread malignant cells.  Do not use CytoLyt Solution.

Breast Aspiration (Cyst fluid, not Fine Needle Aspiration)

·         Collect aspirate in a clean container labeled with the patient’s full name.  Add an equal volume of CytoLyt Solution.  Submit to the laboratory with the completed requisition form. 

 

Gastrointestinal Specimen

The adequacy of the gastrointestinal specimen is determined by the presence of well-preserved epithelial cells indicative of the type present at the site sampled.  All GI specimens will deteriorate rapidly due to enzymatic activity.  In addition, these specimens are easily contaminated by epithelium from sites proximal to that being sampled.   

·         If requesting evaluation for microorganisms prepare direct smears: Brush or roll specimen directly onto a clean slide labeled in pencil with the patient's full name.  Do not fix.  Allow to air-dry.  Deposit brush directly into container of CytoLyt Solution labeled with the patient’s full name and submit to the laboratory.

·         GI fluid: Collect in a clean container labeled with the patient’s full name.  Immediately add an equal volume of CytoLyt Solution.  Submit to the laboratory with the completed requisition form.

 

CSF

·         Collect a minimum of one mL of CSF, preferably two-three mLs, into a clean container labeled with the patient’s full name.  Immediately add an equal volume of CytoLyt Solution.  Submit to the laboratory. 

 

Fine Needle Aspiration

·         Direct Smears: Dispense 1 or 2 drops of aspirate from the needle tip directly onto a clean slide labeled in pencil with the patient's full name.  Prepare “squash” prep by placing a second clean labeled slide on top of the slide with the aspirate and gently pull the slides apart.  One slide is fixed immediately with an alcohol base spray, and the second slide is allowed to air-dry.  The preferred number of passes is a maximum of 4 passes.  Alternate method of slide fixative preparations for each pass.  Please indicate on the requisition form and on the slides if the direct smears are "fixed" or "non fixed".  

·         Drop the remaining cellular material in the same prefilled container of CytoLyt Solution, ensuring that the collection is made from the same body site.  The container is labeled with the patient’s full name.  Submit to the laboratory with the completed requisition form. 

 

 

Cytology Supplies

ThinPrep vials, Gyn collection devices, frosted end slides, slide holders and mailers, CytoLyt Solution, and alcohol base spray fixative are provided at no charge.

 

NOTE:  Please package slides for GYN cytology (Pap smears) and slides for Non-GYN cytology separately from any specimens in formalin.  Do not pack them in the same box.  Fumes from the formalin cause significant artifact, precluding accurate interpretation of the cytology specimen.

 

 

Non-Gyn Cytology Request Form

Click on the link below to view and/or print the Non-Gyn Cytology Request Form.

** Adobe Acrobat Reader must be installed on the computer. **

 

Non-Gyn Cytology Request Form